Dr. Christian Rolfo, now at University of Maryland after training in Argentina, Italy, & other parts of Europe, speaks with Dr. West about his focus on phase I clinical trials & liquid biopsies, and having close connections with people around the world. (42:30)
Dr. Charu Aggarwal from University of Pennsylvania Abramson Cancer Center joins Dr. Jack West to discuss new data on plasma-based testing for tumor mutational burden (TMB) & the current state of liquid biopsies, TMB, & immunotherapy-based options today. (36:57)
Host Dr. Jack West chats with Dr. Stacy Gray, expert in molecular testing patterns and attitudes, about current hurdles in broad adoption of comprehensive testing in cancer care, as well as ways to overcome them. (19:21)
Dr. Jean-Charles Soria reviews the challenge in academic research of “champagne dreams on a beer budget”, his decision to pursue a research leadership role at AZ, & shares his vision of a future of molecular oncology & a growing role for liquid biopsies. (23:39)
Dr. Greg Riely from MSKCC and Dr. Jack West review the changing role for plasma NGS and local ablation therapy (LAT) for oligometastic disease (OMD) or oligoprogressing advanced NSCLC in clinical practice. (28:11)
Dr. West & Charu Aggarwal from University of Pennsylvania reviews data from her own group & other centers, demonstrating increasing practical utility & remaining limitations of liquid biopsy testing for molecular markers in advanced NSCLC. (26:52)
Dr. Jack West connects with Dr. Matthew Gubens of UCSF, discussing practicing oncology in the Bay Area, telemedicine in the cancer clinic, emerging data supportig plasma NGS in advanced NSCLC, & struggling to maintain work-life balance. (20:57)