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Tag Archives: CheckMate 227

Drs. Jack West and Charu Aggarwal: New Data on Liquid Biopsies, Tumor Mutational Burden, and Choosing Optimal Systemic Therapy Today

Dr. Charu Aggarwal from University of Pennsylvania Abramson Cancer Center joins Dr. Jack West to discuss new data on plasma-based testing for tumor mutational burden (TMB) & the current state of liquid biopsies, TMB, & immunotherapy-based options today. (36:57)

March 9, 2020 by BeaconMedIC Posted in West Wind Podcast Tagged Abramson Cancer Center, Beacon Medical Interchange, BeaconMedIC, Cancer, Charu Aggarwal, CheckMate 227, Checkmate-9LA, City of Hope, City of Hope Comprehensive Cancer Center, Education, Guardant, Health, Howard (Jack) West, immunotherapy, IO combinations, Jack West, liquid biopsy, maintenance therapy, Medicine, nivo/ipi, nivolumab ipilimumab, Oncology, pembrolizumab, plasma NGS, Science, TMB, Tumor Mutational Burden, University of Pennsylvania, West Wind, West Wind Podcast

Is Nivo/Ipi the Treatment of Choice for Patients with Advanced NSCLC, Tumor PD-L1 Under 1%, & High TMB? New Data from CheckMate 227 (BMIC-040)

Dr. Jack West reviews data from the CheckMate 227 trial in patients with advanced NSCLC & tumor PD-L1 <1% that suggests potential utility of the nivolumab/ipilimumab (nivo/ipi) combination in patients with low PD-L1 and high tumor mutation burden (TMB). (8:56)

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June 22, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged Advanced NSCLC, Beacon, Beacon Medical Interchange, Cancer, CheckMate 227, Education, H. Jack West, Health, immunotherapy, ipilimumab, Jack West, Medicine, nivo/ipi, nivolumab, Oncology, Opdivo, PD-L1, Science, The Beacon, The Beacon Podcast, TMB, tumor mutation burden, Yervoy

My Top 5 ASCO 2018 Abstracts in Advanced NSCLC (BMIC-036)

Dr. Jack West reviews his top 5 abstracts in the advanced NSCLC track at ASCO 2018, explaining why each is poised to change the landscape of patient care in this setting. (10:17)

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May 21, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged #LCSM, Advanced NSCLC, ASCO, ASCO18, atezolizumab, Beacon, Beacon Medical Interchange, Cancer, CheckMate 227, dacomitinib, Education, EGFR mutation, gefitinib, H. Jack West, Health, immunotherapy, IMpower131, Jack West, KEYNOTE-142, KEYNOTE-407, Keytruda, Medicine, nivolumab, Oncology, Opdivo, PD-L1, pembrolizumab, Science, Tecentriq, The Beacon, The Beacon Podcast

Are Tumor Mutation Burden and Nivolumab/Ipilimumab Ready for Clinical Use? Insights from CheckMate 227 (BMIC-035)

Dr. Jack West reviews the CheckMate 227 trial, summarizing highlights from efficacy & side effects of nivolumab/ipilimumab (nivo/ipi) compared to standard doublet chemotherapy in patients with advanced NSCLC & high tumor mutational burden (TMB). (9:39)

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May 11, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged Advanced NSCLC, Beacon, Beacon Medical Interchange, Cancer, CheckMate 227, Education, H. Jack West, Health, high TMB, immune checkpoint inhibitor, immunotherapy, ipilimumab, Jack West, Medicine, Mut/Mb, mutations/megabase, nivo/ipi, nivolumab, nivolumab/ipilimumab, Oncology, Opdivo, Science, The Beacon, The Beacon Podcast, TMB, tumor mutation burden, Tumor Mutational Burden, Yervoy

Nivolumab/Ipilimumab vs. Chemo in High TMB Advanced NSCLC: Key Results from CheckMate 227 (BMIC-034)

Dr. Jack West reviews the CheckMate 227 trial, summarizing highlights from efficacy & side effects of nivolumab/ipilimumab (nivo/ipi) compared to standard doublet chemotherapy in patients with advanced NSCLC & high tumor mutational burden (TMB). (13:06)

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May 10, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged Advanced NSCLC, Beacon, Beacon Medical Interchange, Cancer, CheckMate 227, Education, H. Jack West, Health, high TMB, immune checkpoint inhibitor, immunotherapy, ipilimumab, Jack West, Medicine, Mut/Mb, mutations/megabase, nivo/ipi, nivolumab, nivolumab/ipilimumab, Oncology, Opdivo, Science, The Beacon, The Beacon Podcast, TMB, tumor mutation burden, Tumor Mutational Burden, Yervoy

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