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Beacon Medical Interchange – BeaconMedIC

Timely commentary on healthcare in general, cancer in particular.

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Monthly Archives: December 2018

Top 5 Most Influential Trial Findings in Lung Cancer Management in 2018 (BMIC-073)

Dr. Jack West summarizes his list of the top 5 most influential trials in lung cancer that reported results in 2018, including why they matter. (13:27)

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December 28, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged atezolizumab, Beacon, Beacon Medical Interchange, Cancer, chemoradiation, chemotherapy, consolidation, durvalumab, Education, EGFR mutation, first-line, gefitinib, H. Jack West, Health, IMFINZI, immunotherapy, Iressa, Jack West, KEYNOTE-189, KEYNOTE-407, Keytruda, Medicine, nab-paclitaxel, NEJ009, non-small cell lung cancer, NSCLC, Oncology, PACIFIC Trial, paclitaxel, pembrolizumab, pemetrexed, Science, SCLC, small cell lung cancer, Tecentriq, The Beacon, The Beacon Podcast

What does the CheckMate-331 trial of nivolumab vs. chemo for relapsed SCLC tell us? (BMIC-072)

Dr. Jack West reviews the trial design, key results, and implications of the CheckMate-331 trial of nivolumab (Opdivo) vs. standard chemotherapy for relapsed small cell lung cancer. (8:57)

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December 21, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged amrubicin, Beacon, Beacon Medical Interchange, Cancer, CheckMate-331, Education, H. Jack West, Health, Hycamtin, immunotherapy, Jack West, Medicine, nivolumab, Oncology, Opdivo, relapsed SCLC, Science, SCLC, small cell lung cancer, The Beacon, The Beacon Podcast, topotecan

The IMpower130 Trial of Carbo/Nab-Paclitaxel +/- Atezolizumab: Does this Positive Trial Change Management? (BMIC-071)

Dr. Jack West reviews the IMpower130 trial of carboplatin + nab-paclitaxel with or without atezolizumab as first line treatment for advanced non-squamous NSCLC and whether this positive trial changes management in this setting. (9:58)

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December 11, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged Abraxane, ALK rearrangement, atezolizumab, Beacon, Beacon Medical Interchange, Cancer, carboplatin, Education, EGFR mutation, Genentech, H. Jack West, Health, IMpower130, Jack West, Medicine, nab-paclitaxel, non-squamous non-small cell lung cancer, NSCLC, Oncology, Roche, Science, Tecentriq, The Beacon, The Beacon Podcast

Overall Survival Benefit for Local Ablative Therapy as Consolidation for Oligometastatic Stage IV NSCLC: Where Does it Fit in Practice Now? (BMIC-070)

Dr. Jack West describes recently updated results of a small randomized trial of consolidation local ablative therapy (LAT) for oligometastatic advanced NSCLC after initial systemic therapy & considers whether these results should shape clinical practice. (9:52)

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December 9, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged Beacon, Beacon Medical Interchange, Cancer, consolidation, Daniel Gomez, Education, H. Jack West, Health, Jack West, LAT, local ablative therapy, Medicine, oligometastatic disease (OMD), Oncology, overall survival, SABR, SBRT, Science, stereotactic ablative body radiation, stereotactic body radiation therapy, The Beacon, The Beacon Podcast

The IMpower132 Trial: Does This Change the Advanced NSCLC Landscape? (BMIC-069)

Dr. Jack West reviews the IMpower132 trial of platinum + pemetrexed with or without atezolizumab as first line treatment for advanced non-squamous NSCLC and where these results fit into management of patients in this setting. (6:38)

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December 4, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged alimta, atezolizumab, Beacon, Beacon Medical Interchange, Cancer, carboplatin, cisplatin, Education, Genentech, H. Jack West, Health, IMpower132, Jack West, Medicine, non-squamous non-small cell lung cancer, NSCLC, Oncology, pemetrexed, Roche, Science, Tecentriq, The Beacon, The Beacon Podcast

The MYSTIC Trial has Failed on Overall Survival in Advanced NSCLC: What Does and Doesn’t This Tell Us? (BMIC-068)

Dr. Jack West reviews the trial design of the MYSTIC trial of durvalumab alone or in combination with tremelimumab, what we know about results, and the implications for the current & future landscape in NSCLC. (9:41)

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December 2, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged AstraZeneca, Beacon, Beacon Medical Interchange, Cancer, chemotherapy, durvalumab, Education, first-line, H. Jack West, Health, IMFINZI, Jack West, Medicine, MYSTIC, non-small cell lung cancer, NSCLC, Oncology, Science, The Beacon, The Beacon Podcast, tremelimumab

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