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Beacon Medical Interchange – BeaconMedIC

Timely commentary on healthcare in general, cancer in particular.

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Monthly Archives: May 2018

My Top 5 ASCO 2018 Abstracts in Stage I-III NSCLC, Small Cell Lung Cancer, & Mesothelioma (BMIC-037)

Dr. Jack West reviews his top 5 abstracts in stage I-III non-small cell lung cancer, small cell lung cancer, and mesothelioma at ASCO 2018, explaining why each is poised to change the landscape of patient care in this setting. (7:12)

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May 23, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged #LCSM, ASCO, ASCO18, Beacon, Beacon Medical Interchange, Cancer, cell-free DNA, circulating tumor DNA, durvalumab, early stage NSCLC, Education, H. Jack West, Health, IMFINZI, Jack West, lymph node dissection, Medicine, mesothelioma, Oncology, rova-T, rovalpituzumab, Science, SCLC, small cell lung cancer, stage I-III NSCLC, The Beacon, The Beacon Podcast, TRINITY trial

My Top 5 ASCO 2018 Abstracts in Advanced NSCLC (BMIC-036)

Dr. Jack West reviews his top 5 abstracts in the advanced NSCLC track at ASCO 2018, explaining why each is poised to change the landscape of patient care in this setting. (10:17)

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May 21, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged #LCSM, Advanced NSCLC, ASCO, ASCO18, atezolizumab, Beacon, Beacon Medical Interchange, Cancer, CheckMate 227, dacomitinib, Education, EGFR mutation, gefitinib, H. Jack West, Health, immunotherapy, IMpower131, Jack West, KEYNOTE-142, KEYNOTE-407, Keytruda, Medicine, nivolumab, Oncology, Opdivo, PD-L1, pembrolizumab, Science, Tecentriq, The Beacon, The Beacon Podcast

Are Tumor Mutation Burden and Nivolumab/Ipilimumab Ready for Clinical Use? Insights from CheckMate 227 (BMIC-035)

Dr. Jack West reviews the CheckMate 227 trial, summarizing highlights from efficacy & side effects of nivolumab/ipilimumab (nivo/ipi) compared to standard doublet chemotherapy in patients with advanced NSCLC & high tumor mutational burden (TMB). (9:39)

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May 11, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged Advanced NSCLC, Beacon, Beacon Medical Interchange, Cancer, CheckMate 227, Education, H. Jack West, Health, high TMB, immune checkpoint inhibitor, immunotherapy, ipilimumab, Jack West, Medicine, Mut/Mb, mutations/megabase, nivo/ipi, nivolumab, nivolumab/ipilimumab, Oncology, Opdivo, Science, The Beacon, The Beacon Podcast, TMB, tumor mutation burden, Tumor Mutational Burden, Yervoy

Nivolumab/Ipilimumab vs. Chemo in High TMB Advanced NSCLC: Key Results from CheckMate 227 (BMIC-034)

Dr. Jack West reviews the CheckMate 227 trial, summarizing highlights from efficacy & side effects of nivolumab/ipilimumab (nivo/ipi) compared to standard doublet chemotherapy in patients with advanced NSCLC & high tumor mutational burden (TMB). (13:06)

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May 10, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged Advanced NSCLC, Beacon, Beacon Medical Interchange, Cancer, CheckMate 227, Education, H. Jack West, Health, high TMB, immune checkpoint inhibitor, immunotherapy, ipilimumab, Jack West, Medicine, Mut/Mb, mutations/megabase, nivo/ipi, nivolumab, nivolumab/ipilimumab, Oncology, Opdivo, Science, The Beacon, The Beacon Podcast, TMB, tumor mutation burden, Tumor Mutational Burden, Yervoy

KEYNOTE-189: Clinical Implications in Patients with Advanced Non-Squamous NSCLC and Negative (<1%) Tumor PD-L1 Expression (BMIC-033)

Dr. Jack West reviews clinical results in patients with advanced non-squamous NSCLC and negative (<1%) tumor PD-L1 on the KEYNOTE-189 trial, providing thoughts on the clinical implications of these findings in management of this patient subset. (6:31)

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May 4, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged 1-49%, Advanced NSCLC, Beacon, Beacon Medical Interchange, Cancer, carboplatin, chemo-immunotherapy, chemoimmunotherapy, cisplatin, Education, H. Jack West, Health, immune checkpoint inhibitor, immunotherapy, Jack West, KEYNOTE-021g, KEYNOTE-189, Keytruda, low PD-L1, Medicine, non-squamous, Oncology, pembrolizumab, pemetrexed, Science, The Beacon, The Beacon Podcast, TPS, tumor proportion score

KEYNOTE-189: Clinical Implications in Patients with Advanced Non-Squamous NSCLC and Low (1-49%) Tumor PD-L1 Expression (BMIC-032)

Dr. Jack West reviews clinical results in patients with advanced non-squamous NSCLC and low (1-49%) tumor PD-L1 on the KEYNOTE-189 trial, providing thoughts on the clinical implications of these findings in management of this patient subset. (6:15)

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May 4, 2018 by BeaconMedIC Posted in The Beacon Podcast Tagged 1-49%, Advanced NSCLC, Beacon, Beacon Medical Interchange, Cancer, carboplatin, chemo-immunotherapy, chemoimmunotherapy, cisplatin, Education, H. Jack West, Health, immune checkpoint inhibitor, immunotherapy, Jack West, KEYNOTE-021g, KEYNOTE-189, Keytruda, low PD-L1, Medicine, non-squamous, Oncology, pembrolizumab, pemetrexed, Science, The Beacon, The Beacon Podcast, TPS, tumor proportion score

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